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Role of inactivity in chronic diseases (2017)

evolutionary insight and pathophysiological mechanisms

Overall, physical inactivity is an underappreciated cause of almost all chronic diseases/conditions, whose outcome increases mortality and decreases healthspan. Remarkably, physical inactivity speeds biological aging, and physical inactivity gene identification will be a future challenge to help decrease inactivity-induced chronic disease and improve the health and well-being of our society.

Literatuurverwijzing: Booth, F.W., Roberts, C.K., Thyfault, J.P., Ruegsegger, G.N., & Toedebusch, R.G. (2017). Role of inactivity in chronic diseases: evolutionary insight and pathophysiological mechanisms. Physiological reviews 97 (pp. 1351–1402)